The News Caravan

Tag: scientist

  • Kashmir’s AIIMS Scientist Leads Major Cancer Breakthrough

    [ad_1]

    by Faiqa Masoodi

    SRINAGAR: In a major breakthrough, a Kashmiri scientist along with a group of European scientists has discovered a new potential drug for the treatment of metastatic hypoxic cancers. The drug is currently in an advanced stage of further investigations post-animal trials.

    Dr Musadir Nabi Peerzada
    Dr Musadir Nabi Peerzada (AIIMS)

    Hailing from Muqami Shahwali in Kupwara’s Drugmulla belt, Dr Mudasir Nabi Peerzada led a team of eminent European scientists and co-workers to discover a new drug for the treatment of various metastatic hypoxic cancers.

    Dr Peerzada who is currently working as a C-Level scientist at AIIMS New Delhi, has completed his postdoctoral training at the National Institute of Pathology. He was awarded a prestigious postdoctoral fellowship by the Indian Council of Medical Research (ICMR), Department of health research, Government of India.

    The discovery is believed to help in silencing the HIF-1 factor-controlled human CAIX and CAXII activity in cancerous cells. The hCAIX and hCAXII are overexpressed in the renal, pancreatic, gut, oral, brain, lung, and ovarian cancers, therefore the drug could be significant in treating multiple cancers with greater efficacy.

    Dr Mudasir said that he and his team strenuous efforts for many years to make this path-breaking discovery. The drug has shown satisfactory results in various tumour models and is currently undergoing advanced investigations.

    “This discovery took us years of tests and trials. We tested it on animals before going ahead,” Dr Peerzada said, adding that the drug is undergoing advanced clinical trials for further investigation.

    The study was published in ACS Medicinal Chemistry Letters entitled Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors was published on May 8, 2023.

    He said that the new findings are remarkable in curing hypoxic cancers and will be a boon for cancer-related research.

    The other scientists who are part of this invention include Dr Alessandro Bonardi, Dr Niccolò Paoletti, Dr Daniela Vullo, Dr Paola Gratteri, Dr Claudiu T Supuran, and Dr Amir Azam

    Dr Peerzada is working on the development of anti-cancer therapeutics discovery taking into account the ATP binding site of kinases, hCAIX, hCAXII activity, cycle arrest at the G2/M phase of mitosis, prevention of HER2 dimerisation to deregulate PI3K/AKT and MAPK cell signalling pathways.

    [ad_2]
    #Kashmirs #AIIMS #Scientist #Leads #Major #Cancer #Breakthrough

    ( With inputs from : kashmirlife.net )

  • Future ChatGPT models to replace many human tasks: Top AI scientist

    Future ChatGPT models to replace many human tasks: Top AI scientist

    [ad_1]

    New Delhi: The future versions of ChatGPT have the potential to replace many tasks currently performed by humans, leading AI researcher and cognitive scientist Ben Goertzel has warned.

    Known for co-developing Sophia the Robot, Goertzel believes the new large language models that power generative AI will transform the world, reports ZDNet.

    “You don’t need to be incredibly creative and innovative or make big leaps to do most people’s jobs, as it turns out,” Goertzel was quoted as saying.

    MS Education Academy

    Automated AI tools could lead to industry reshuffling and reassigning job duties.

    Drive-through fast-food workers, copy editors and designers are already impacted by AI.

    “Tools like Grammarly decrease the need for human copy editors,” Goertzel said.

    China-based marketing and public relations agency BlueFocus is replacing third-party copy writers, designers, and short-term contractors to fully embrace generative AI like ChatGPT.

    After the ChatGPT success, apps with the term ‘AI Chatbot’ or ‘AI Chat’ in either their app name, subtitle, or description on both Google and Apple app stores have increased a whopping 1,480 per cent (year-over-year) in the first quarter this year.

    According to analytics firm Apptopia, just this year (through March), 158 such apps have arrived on the app stores.

    However, jobs where the essence is human contact, like preschool teachers, political strategists and artists, “will not become obsolete”.

    Today’s generative AIs “are able to impersonate general AIs by just having such a broad variety of training data. They don’t have to go far beyond that training data to do amazing stuff. It’s a testament to the power of computer networks and multi-GPU server farms,” he was quoted as saying.

    [ad_2]
    #Future #ChatGPT #models #replace #human #tasks #Top #scientist

    ( With inputs from www.siasat.com )