Tag: interview

  • ‘We Must Look at Our Past with All Its Dissensions, Pain-learn and Understand the Perils of Sectarianism’

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    With PhD from the Delhi School of Planning and Architecture (1999) and a post-doctorate from Massachusetts Institute of Technology (2022), Dr Hakeem Sameer Hamdni’s The Syncretic Traditions of Islamic Religious Architecture of Kashmir (Early 14th –18th Century) filled a huge void that in Kashmir’s architectural history. Design Director at the INTACH Kashmir, his latest book Shi’ism in Kashmir: A History of Sunni-Shia Rivalry and Reconciliation is a daring attempt to probe an issue that no scholar has touched ever. A week after the book release, in a freewheeling interview, Sameer details why he choose the subject and what are the net outcomes for Kashmir

    TheNewsCaravan (KL): You are a trained architect with a specialisation in Islamic architecture. You did an excellent book on Kashmir’s medieval architecture that filled a wide gulf after a very long time. What prompted you to get into a very sensitive topic involving Kashmir’s sectarian tensions, an issue that attracted almost no scholar, so far?

    HAKIM SAMEER HAMDANI (HSH): That is a question that is asked of me a lot, now that the book has been released. So how do I answer it? Well, let me start by saying that as you rightly pointed out my last book was on the Muslim Religious Architecture of Kashmir. And, it was during that very process of researching, I got interested or maybe intrigued by how our historiography has been used as a conscious tool in framing narratives which project the past as a milieu of religious and sectarian conflict.

    This is especially true when we speak about a Shia or a Sunni society during the medieval or even early modern period but then this binary broadly covers how we also perceive Hindu-Muslim relations in the region. But then how historical is this narrative of an antagonistic past?

    I do accept that our past is not one which upholds liberal representation, but then the material culture linked with it is replete with examples of what we could call negotiated pragmatism and co-existence. Unfortunately a great deal of our textual history, particularly in the genre of tazkiras (hagiographies) coming as it does from competing centres of power and patronage, often conflates symbols of belonging to a privileged class with religious or sectarian discrimination.

    Also, the idea that the book breaches a sort of taboo in our society – a topic which can create divisions is something that I don’t personally agree with. In a way, this ‘let’s not talk about these problematic issues’ assumes that either as a society we are incapable of dealing with sensitive subjects or that as researchers we are so grounded in our own biases and prejudices that the task is virtually unachievable.

    I disagree. I am of the view that we have the individual (if not institutional) capacities to as I said in another interview, “historicize or rather contextualize our past in a way that does not seek not-to-hide from differences- but also search, explore for shared similarities- similarities that made us Kashmiris”. That was the origin of a book which engages with a layered past and complex moments of our history with competing interests.

    I may be repeating myself here, but to survive as a people, as a civilisation, we need to look at our past with all its dissensions,  pain-learn and ensure that we and our future generations will understand and realise the perils of sectarianism, just like communalism are too real and too near to be ignored. We also need to understand that differences will exist and where they exist, they need to be celebrated, not hidden behind a veil of assumed unity and uniformity.

    KL: Kashmir’s transition to Islam is well-researched and documented. Would you shed some light on the history and evolution of Shia Islam, or what you call, Shia’ism in Kashmir?

    HSH: If I may, I would rather contest this understanding. Yes, we have texts which account for the beginning of Muslim rule in Kashmir. But, this beginning of Muslim presence in Kashmir is still a rather grey area. We have narratives enshrined in texts which came in existence in the sixteenth, seventeenth or even eighteenth century as is the case with Khwaja Azam Dedhmari’s Vaqiati Kashmir, and these texts serve as our only basis of understanding the formative period of Muslim society in Kashmir. So a text like Baharistani Shahi or Tarikh i Kashmir of Malik Haider coming as they do from a Shia space would make us understand that the first Muslim saintly figure of the region Bulbul Shah was a Shia. But then, let us say from the genre of tazkirah, an early account such as Tazkira-i-Airifin of Baba Ali Raina would contest this, and locate early Muslim presence in Kashmir firmly in a Sunni space.

    So we have these contesting latter-day texts, some written more than four centuries after the actual event, which forms the basis from which we seek to contextualise the beginning and the nature of Muslim beginning in Kashmir. Academically this has all the making of a grey zone.

    Hakim Sameer Hamdanis book on Kashmirs sectarian reconcilation being launched in Srinagar in March 2023. KL Image Fayaz Ahmad Najar
    Hakim Sameer Hamdani’s book on Kashmir’s sectarian reconcilation being launched in Srinagar in March 2023. KL Image Fayaz Ahmad Najar

    Additionally, these texts also seek to firmly locate the beginning of Muslim society in their respective sects. The same is the case of the Nurbaksiyya Sufi order, which emerged in Kashmir during the closure of the fifteenth century. The founder of this order in Kashmir, Mir Shamsuddin Iraqi is seen in most Sunni accounts as the progenitor of Shi’ism in Kashmir, but it is difficult to establish the nature of his Shi’iness. That is why I do write in the introduction that the contours of Shiism during the Sultanate period are not sufficiently explained.

    But then my book is not about the medieval period, it explores the nineteenth century instead. So hopefully someone in near future explores these early days of Muslim society in Kashmir beyond modern narratives, which have become frankly repetitive in their narratives.

    KL: You briefly talk about revered Shia and Sunni figures. How do you approach how they are represented in histories with miracles directed against the other community?

    HSH: Well, I believe that we judge or rather contextualise these events – these miracles in the mizaj of their occurrence not in their objective reality, nor considering our personal beliefs or biases. That has been my approach.

    KL: Most of the biased or neutral histories source Kashmir’s sectarian tensions to the 32 years of Chak Rule. There are contested narratives on this. But what is your scholarship revealing because you are a scholar who does not go by hearsay or unsubstantiated events of history?

    HSH: Not Chak rule, rather if we were to make an argument for a certain contestation based on the confessional identity of communities it would start during the fag end of the Shahmiri rule. The first recorded case we have of someone seeking to make Kashmir into a single denominational community is that of the Mughal conqueror, Mirza Haider Dughlat. In fact, he proudly states this in his own history, Tarikh-i Rashidi.

    But then some of these sectarian contestations that originate in Dughlat’s court make themselves a part of the court politics in the Chak rule also. We have the execution of Qazi Musa during Yaqoob Shah Chak’s brief rule but then even Shia sources; Baharistan as well as Haidar Malik condemn his execution.

    Conversely, you have two famous qasidah’s of Baba Dawood Khaki, the principal khalifah of the Suhrawardi saint, Shaykh Hamza Makhdoom, which celebrates Chak rulers, including Yosuf Shah as well as his uncle Husain Shah Chak. Also, we have intermarriage between ruling elites happening all through this period across any perceived sectarian fault line.

    Sameer Hamdani book on Kashmir Shia Sunni relations 2023
    Sameer Hamdani book on Kashmir Shia Sunni relations (2023)

    A Sunni-centric text, such as the tazkira of Baba Haider Tulmulli writes about two wives of Hussain Shah Chak who were not only Sunnis but also linked in a spiritual line of discipleship to Shaykh Hamza Makhdum. Then again we have the famous case of Habba Khatoon – who is a Sunni, though, like other women poetesses of Kashmir, you cannot locate her in contemporary texts.

    So what I am trying to say is yes there are tensions, but then that is not the only history of that period. But, again let me clarify this book is not about medieval Kashmir, I only briefly touch on the period in trying to locate projections of a contested past.

    KL: How did the power-play exhibit in the Mughal era of Kashmir after Chak’s were ousted from power? How correct is the notion that the Mughals persecuted Shia Muslims?

    HSH: The renowned historian, Irfan Habib does link Akbar and the religious elite at his court with a sectarian, restrictive attitude towards the Shi’a till say around the early 1570s. The execution of Mirza Muqim Isfahani and Mir Yaqub, the envoys sent from Husain Shah Chak to the Mughal court by Akbar can be seen as a part of that attitude. But Kashmir was conquered in 1586 and the emperor proclaimed Din-i-Illahi in 1582. So it was a different Akbar. The conquest of Kashmir does have a certain sectarian undertone but the affair should be seen as part of the gradual process of expansion of centralised authority with vastly superior resources and a borderland region.

    The relation between Delhi and Kashmir marks this tension between an expanding centre and a periphery in which, the result occurred on expected lines. Were the Mughals sectarian? No. Despite the bad press that they are getting these days, the Mughals were only interested in one profession ‘rulership’. Their notions of royalty almost overlap with the western notion of the divine right to rule. Jehangir in his comparison between court politics in Istanbul, Isfahan and Agra clearly speaks how unlike in Ottoman Turkey or Safavid Iran, Mughal India was open to both Sunnis and Shias. And, we find presence of Shia subedars or naib-subedars in Kashmir- Iteqad Khan, Abu Nasr Khan, Muzaffar Khan, Zafar Khan Ahsan, Ali Mardan Khan, Ibrahim Khan, Fazil Khan, Hussain Beg Khan, Qawam-ud Din Khan, Abu Mansur Safdar Jung, Afrisiyab Khan.

    One should also realise that when the Mughals sought to conquer Kashmir, they were engaged in repeated battles with Kashmiri soldiers – a majority of whom were Shia. We have Jehangir writing about the traders of Kashmir hailing from the Sunni community and the soldiers belonging to the Shia and Nurbakshiyya communities. So in these circumstances, an event like the massacre of the Kashmiri soldier by the Mughals at Macchbawan can be seen as a massacre of Shias because they figured prominently in the Kashmiri army. But that would be a wrong reading. This was a massacre of Kashmiri soldiers seen as a threat to the Mughal Empire who were also Shia.

    Sheikh Mohammad Abdullah in prayers somewhere in Kashmir perihery and apparently during a visit
    Sheikh Mohammad Abdullah in prayers somewhere in Kashmir periphery and apparently during a visit

    Again in the reign of Shah Jehan, we have the case of Khawja Khawand Mahmud Naqshbandi who was a Sufi shaykh, connected with the imperial family but was nevertheless banished from Srinagar because of his involvement in a Shia-Sunni riot. Also, a major Shia polemical work against the Sunnis, Al Biyaz-i-Ibrhami was authored in Kashmir under the direct patronage of the subedar, Ibrahim Khan. Yes sometimes the Shia would find themselves under restrictive circumstances but this was mostly a result of individual predilections of the subedar or even the emperor. It is only when we come to close to Mughal rule, with its collapse of central authority that the Shia get targeted because of their faith and also face riots.

    KL: What was the state of sectarian tensions in the Afghan rule that is usually seen as oppressive across all sects?

    HSH: As you said it was oppressive for all, but at certain moments it could and was more oppressive towards the Shia – also the Hindus. But then we also find the presence of a Shia subedar, Amir Khan Jawan Sher and Kifayat Khan. The Qizilbash component in the Afghan is also indicative of Shia presence though non-native.

    The only instance of a prominent Kashmiri figure rising in the Afghan court is Mulla Hakim Jawad, whose son Mulla Hakim Azim would then serve as the chief physician at the court of the Sikh subedar, Shaykh Ghulam-ud Din and consequently Dogra ruler, Maharaja Gulab Singh. Also, under Afghans, we find the presence of a substantial contingent of Iranian Shia traders in the city who also patronised the native Shia community. But, like everything else, the Afghan period is a mixed bag for Kashmir and for the Shia, it is more on the oppressive side.

    KL: Your book is focussed on nineteenth-century Kashmir. The era was an extension of Sikh rule in a way. What were the factors that led to the reconciliation between the different Muslim sects? How did it happen?

    HSH: In the end, it is a gradual realisation that whether we see ourselves as Shia or Sunni, we are equally discriminated against, and seen as outsider Muslims by the court. The Shia-Sunni faultline is detrimental to our Muslim existence. It is a gradual process but once it commences – gradually from the community elite on either side, it does capture the imagination of the religious classes and more importantly the new class of educated Muslim youth. There are tensions on the way, but the Muslim fight against, what is perceived, as Hindu rule forms the basis of an ecumenical movement within the Kashmiri Muslim community.

    KL: Who were the major players in the reconciliation process and what were the key events that exhibited the reconciliation?

    HSH: There are many players – you could say the initial interaction between Mirwiaz Rasul Shah and Moulvi Haider Ansari did help in toning down the sectarian faultiness within the city to a level where they could be managed. Also individuals from the dynasty of Mufti Qawamuddin, also Aga Sayyid Musavi who is said to have visited revered Sunni shrines of Kashmir, at Char-I Sharif and Dastgir Sahab.

    sameer1
    Hakim Sameer Hamdani (author)

    But, the figure who, in a way, formalises this process is Khawja Saaduddin Shawl. He does emerge as a visionary, who is working towards the formulation of Muslim political consciousness in Kashmir. In 1873, we had the last major Shia-Sunni riot in the city, and within a decade we saw Shawl working to tone down sectarian tensions in the city while also voicing Muslim grievances, hopes-aspirations. This outreach is positively welcomed by the Shia and the main figurehead who emerges in this engagement on the Shia side is Aga Sayyid Hussain Shah Jalali.

    As we move towards the first decade of the twentieth century, we see that Shia elders, Aga Sayyid Husain Jalali and Hajji Jaffar Khan sign the memorandum of grievances authored on behalf of the Kashmiri Muslim community in 1907. Similarly, when after the disturbances in the Sericulture department, the durbar bans the daytime Ashura procession in 1924, Shawl helps Jalali in taking out a daytime procession in defiance of the order. This is the first Shia-Sunni march highlighting Muslim unity and was accompanied by two alams (standards) from the revered shrine of Asar-i-Sharif Kalashpora. The move is reciprocated by the Shia who also participate under Jalali’s leadership in the procession from Khanqah-i-Mualla to Char-i-Sharief.

    This coming together of the two communities is also witnessed during the BJ Glency Commission of Inquiry in 1931, when the Shia representative, Mulla Hakim Muhammad Ali completely aligns with the demands of the Muslim Conference. In fact, he argues that the Muslim Conference is the sole representative of Kashmiri Muslims, Shia and Sunni alike.

    You also see the involvement of Shia Youth in the formulation leading up to, and then in the Reading Room. We have three brothers, Hakim Ali, Hakim Safadr and Hakim Murtaza who are deeply involved with this process. The three are also involved with the organization of Ali Day at Zadibal, which also saw the representation of Kashmiri Sunnis.

    I mean a decade earlier Zadibal would be an area avoided by most Sunnis from the city and now you have this public participation in commemorative events taking place in the heart of a Shia space. And, we have individuals such as Justice Sir Abdul Qadir of Lahore from Anjuman-i-Himayt-ul Islam, Raja Ghazanfar Ali of All India Muslim League.

    And, then as we move into the 40s, individuals like Munshi Muhammad Ishaq or Aga Shaukat who become associated with this Muslim voice. And then those countless people who unfortunately are never named in histories, but whose contribution is so essential to any social or political movement.

    KL: How did the reconciliation display itself post-1931, even though your scholarly work stops in that era, history, as you know, is continuity and sometimes flat.

    HSH: Well as you rightly said the period from 1931 onwards is not a subject of my research but yes if you look at some pivotal moments in Kashmiri history post-47, like the Moi-Muqqadas Tahreek you would find active participation of major Shia figures such as Moulvi Abbas Ansari from Srinagar and Aga Sayyid Yusuf of Budgam. Also, the engagement of various scholars and academicians on various societal or religious issues is very visible.

    You also find Sheikh Muhammad Abdullah playing a pivotal role in organising a single Ashura procession in the city – an event which was otherwise marked by rival processions between competing religious families within the Shia community. And, then the 1990s threw altogether new challenges and a new set of responses.

    KL: For more than half of the millennium, Persian remained the lingua franca of Kashmir to the extent that the rise of Persian led to Kashmir being called the Iran-e-Sageer. Kashmir produced countless Persian intellectuals and poets. How did this Kashmir-Iran relationship impact the sectarian peace or conflict in history?

    HSH: There is a Persian poet, who was Shah Jahan’s poet laureate who is also incidentally buried in Mazzar-i-Shura, Drugjan. A Shia, Qudsi is remembered for his naat in praise of the Prophet, Marhaba Sayyid-Ii-Makki Madaniul Arabi– a naat which was regularly recited on mehfil-i-malud amongst Kashmiri Sunnis. I have been told that occasionally it is still recited.

    Similarly, we find that the majalis and lessons of masters such as Muhsin Fani, Ghani Kashmir, Mulla Sateh, Lala Malik Shaheed and countless others were attended by people and aspirants across sectarian identities. Ali Mardan Khan and Zaffar Khan Ahsan, both of Iranian origin are celebrated for the promotion of literature. Their sessions were attended by people across any sectarian or communal faultline and then helped in permeating the Persian language amongst sections of the Kashmiri population. Works on ethics, poetics, grammar and a host of other subjects compiled in Persian were studied and circulated without any bias of sect or sectarian identity. I have seen numerous Shia libraries which include codices of tafsir work in Persian that originate in the Sunni circles. Similar is the case in the field of calligraphy, which emerged as a major art form in the early modern period in Kashmir.

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    ( With inputs from : kashmirlife.net )

  • GMC Rajouri Walk in Interview

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    GMC Rajouri Walk in Interview

    Date of interview : 15.03.2023

    Timing of Interview : 11:00 AM

    Applications on prescribed format are invited from permanent resident/Domicile of UT of J&K, Non-PSC doctors who are eligible for the post of Junior Resident on tenure basis initially for a period of six (06) months extendable for further period on satisfactory performance under relevant rules. The forms can be had from the office of the undersigned on production of Bank Draft of Rs. 500 (Rupees Five Hundred Only) from the J&K Bank Limited pledged to the Principal Govt. Medical College, Rajouri.

    ELIGIBILITY CRITERIA :

    The candidate must have done MBBS from any recognized institution and been registered with MCI/NMC or J&K Medical Council.

    DOCUMENTS REQUIRED

    APPLICATIONS SHOULD BE ACCOMPANIED WITH ATTESTED COPIES OF THE FOLLOWING DOCUMENTS:

    1. MBBS certificate from 1st to final year MBBS.

    2. Attempt certificate of 1st, 2nd, Pre-fmal and Final MBBS issued by concerned Universities.

    3. MBBS degree and MCI/NMC or State Medical Council registration certificate

    4. Internship completion certificate.

    5. Distinction/National scholarship/Honours/Medals/Academic Merit Certificate if any.

    6. House-job (Jr.) certificate issued by concerned Principal or Equivalent authority.

    7. Date of Birth Certificate.

    8. Permanent Resident Certificate/ Domicile Certificate.

    9. FMGE certificate in case of MBBS degree from outside the country.

    SELECTION CRITERIA

    The selection of the candidates will be made as per the guidelines prescribed by the Government subject to amendment by the Govt, from time to time. Only those candidates who will have permanent registration certificate from the state Medical Council or MCI/NMC will be eligible for applying.

    The final selection of candidates is subject to availability of vacancies at the time of interview. The decision of the selection committee in all matters would be final.

    Other Conditions : 

    The appointee shall be required to submit an affidavit duly attested by the judicial Magistrate at the time of joining to the effect that he/she will not leave the residency mid-way and will serve for the tenure period of 06 months.

    The appointees shall be paid salary in terms of S.O 364 of 2020 Dated: 27.11.2020.

    Appointed/Serving Junior Resident intending to leave the Job shall have to provide one-month prior notice duly forwarded by the concerned HODs or else he/she shall have to deposit one month salary in the institution.

    No experience certificate shall be issued for the tenure service of less than six (06) months.

    No TA/DA shall be admissible for appearing in the interview.

    This is without any prejudice to any writ petition pending before any Hon’ble Court.

    Further Details :

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    ( With inputs from : The News Caravan.com )

  • ‘Some Haakh Varieties Have High Anticancer Potential against Prostate and Lung Cancer Cells’

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    A junior scientist at SKUAST-K, Dr Khalid Zaffar Masoodi is an award-winning biotechnologist who has been working on cancer biology. Founder of Kashmir’s first faculty-led biotech company of Kashmir, Cashmir Biotech Pvt. Ltd, he has been working on low-cost, healthy, non-toxic, and safe designer foods to cure and prevent various disorders including cancer through futuristic functional foods. Currently, his laboratory’s research is related to the identification of anticancer molecules for prostate cancer from medicinal plants endemic to Kashmir. In a freewheeling interview with Masood Hussain, he offers his knowledge about awareness to deliver and contribute new innovations in biotechnology and research on the causes, treatment and prevention of cancer through anticancer functional foods, designer foods, and superfoods.

    TheNewsCaravan (KL): The conventional wisdom is that local issues have local solutions. Can we have local solutions to local health issues as well?

    Khalid Z Masoodi (KZM): There are more than 200 types of cancer throughout the world and we can classify cancers according to where they start in the body, such as breast cancer ovarian cancer, prostate cancer, lung cancer etc. We can also group cancer according to the type of cell they start in and these cancers are increasing day by day worldwide. 20 per cent of these cancers are genetic in origin according to studies and 80 per cent are caused by environmental factors, food habits and lifestyle changes. These factors mutate the DNA and cause changes in normal cell growth.

    For example, our bodies intake 210 mcg per day of cancer-causing hormone-disrupting chemical phthalates found in every soft and flexible plastic we use in our daily life. The beverages in the plastic bottle are injurious as these plastic containers have phthalates that bind to endocrine receptors and overexcite them resulting in malignancies.

    In dark chocolates toxic metals are lurking, it is a state of serious concern as they cause cancer. Preservatives used in foods contain carcinogenic components. Every single person consumes 150 pounds or 60-88 kg of preservatives in a year. Most of the preservatives’ in vogue contain acrylamide which is carcinogenic. The most popular fast food of today’s generation is French fries, potato chips, pizza, and cold drinks in which the presence of Acrylamide and glycidamide has been found. Burgers contain Heterocyclic aromatic amines (HCAs) and polycyclic aromatic hydrocarbons (PAHs). Studies show HCAs and PAHs cause changes in DNA that may increase the risk of cancer. Pizza preservatives – TBHQ and BHA, has been identified as human carcinogen. 1n 2016 as we all know potassium bromate used to soften bread and in many other food items was banned in India as they were found carcinogenic during the course of research.

    The estimated numbers of cancer in 2022 were 17 per cent in the case of breast cancer, 14 per cent in prostate cancer, 4.9 per cent in thyroid cancer, and lung cancer was estimated to be 14.3 per cent worldwide. Prostate cancer is the second leading cause of cancer-related deaths and the primary diagnosed cancer in men. No defined therapy against prostate cancer is present. Drugs cease to function after treatment in most cases. There is a need to cure and prevent deadly diseases with a healthier approach.

    We define here the concept of Designer Foods that have added health benefits. Designer foods are normal foods fortified with health-promoting ingredients. These foods are similar in appearance to normal foods and are consumed regularly as a part of the diet. These foods are safe, non-toxic, organic, are cost-effective while the drugs available are cost-extensive and unaffordable by the majority classes of society and have added off-target effects.

    We believe that a smart diet containing anticancer small molecules and molecules that can treat these disorders can help prevent these disorders The changing food habits of the modern world have changed, from green food (green vegetables), and herbs, to fast food, which is the main concern. We have experimentally shown that these greens, underutilised plants have high antioxidant properties. Some of our studies found some Haakh varieties have high anticancer potential against prostate and lung cancer cells.

    KL: Can you tell us about your academic journey?

    KZM: I completed my schooling at Burn Hall School, Srinagar and continued further studies at AMU. I completed my BSC (Hons) in Botany from AMU and pursued MSc and PhD in Plant Biotechnology from Jammu University under the mentorship of Prof Manoj K Dhar, former VC, University of Jammu, which I completed in 2010.

    KL: What were the takeaways from your PhD?

    KZM: During my PhD, I worked on the reconstruction of carotenoid biosynthetic pathway genes from purple-black carrot (Daucuscarota L). We successfully engineered E Coli that produced Lycopene and beta-carotene. Besides, we increased the production of these carotenoids using the Amplification Promoting Sequence, which increased the copy number of genes and hence their transcription and translation. We also worked on anthocyanins that act as effective natural food bio-colourant and real-time indicators of food spoilage that later helped in developing a smart gel that changes colour with a change in pH and can be used in food industries, biomedical industries and agriculture industries. Synthetic food colours pose a greater threat to humans and are responsible for causing various types of cancers and cardiovascular diseases.

    KL: You continued your post-doctorate in the same field or we changed the subject?

    KZM: The main expertise in cancer biology was gained during my post-doctoral associateship at the University of Pittsburgh, Pennsylvania, USA. There, I simultaneously worked on many projects related to gene and drug discoveries against prostate cancer.

    We found the role of many genes in prostate cancer progression like ELL2, DHX15, PABPCA, EAF2, PRP8 etc. I also helped discover new androgen receptors targeting small molecules. I also increased the efficacy of IADT, the study which came out in the Journal of Urology, Journal of Endocrinology, Oncogene, Molecular Cancer Therapeutics, and PLoS One.

    After my return from the USA, I worked as a Senior Resident at SKIMS, Soura for a short time before joining the Division of Plant Biotechnology, SKUAST-Kashmir as an Assistant Professor. The takeaway for me was that cancer cells are smart and if you try to target them through inhibition of the AR pathway they will salvage their survival through the PI3Kinase pathway. In metropolitan India, prostrate is now the third diagnosed cancer.

    KL: You worked on cancer and then joined SKUAST-K which is all about agriculture. Is not it an interesting twist in the story?

    KZM: It is always a challenge but biotechnologists revolve around the central dogma of molecular biology so DNA, RNA and proteins are the same which makes every organism. Upon my joining SKUAST-K, I surveyed various regions of Jammu and Kashmir to utilize the rich flora for new therapeutics against cancer.

    It is very important that we do translational research that can result in an end product that can be commercialized and can be more useful than a mere publication or a patent. We knew that 60 per cent of the drugs in the market are plant-based or their analogues.

    A rich repertoire of around 3054 medicinal and aromatic plant species (MAPs) are endogenous to Kashmir but were not explored for anticancer properties against prostate cancer through transcriptomics and AR targeted approach earlier. In a drug discovery programme initiated at SKUAST-K funded SERB, we screened 25,000 medicinal plant extracts from Kashmir’s around 350-400 medicinal plants. It resulted in the discovery of 16 new anticancer molecules against prostate cancer. Of these 16 molecules, five were from edible underutilised plants. Our laboratory has filed eight patents in the last three years.

    Dr Khalid Zaffar Masoodi SKUAST
    Dr Khalid Zaffar Masoodi (SKUAST)

    KL: Is there something that you can share with us about the new molecules you discovered?

    KZM: The molecule SKIDDDL-1 present in the TaxO was the best among all the edible plants, which has been consumed for ages in Kashmir as a food supplement and as a vegetable. Over time, however, its use has diminished. This molecule effectively targeted androgen receptors in prostate cancer and decreased cellular progression, cancer cell migration (metastasis) in vitro and reduced tumour volume, and doubled the life expectancy in the mice xenograft model. A smart diet may help reduce the risk of developing prostate cancer, slow the progression of the disease, and prevent invasiveness and metastasis.

    Awaiting a patent, we designed Magic Foods – a range of safe, non-toxic, plant-based anti-prostate cancer futuristic functional foods fortified with our secret TaxO that can be consumed on daily basis by populations worldwide that are at high risk of getting this peculiar cancer. The technology is cheap, safe and has no side effects.

    Since SKUAST-K is the first Farm University to implement NEP 2020, now the faculty is permitted to have a start-up. I was joined by my two MSc students as directors of the faculty-led start-up. They are still studying but are job providers at the same time.

    When we were doing this research, we had a great visitor from the University of  Buffalo, Prof Samina Raja. We thought we can give something better to humanity if we worked together. So we have one collaborative project Haakh.

    I am glad to share that soon you will have an anticancer Haakh variety. We are in the final stages of assessment and experimentation and after a thorough study of about 70 different variants of haakh we found some variants that have good activity against lung and prostate cancer.

    The American University provided us with a small grant which we utilised in DNA bar-coding our Haakh, which can be accessed through GenBank. SERB, DST, Government of India has been kind enough and given me three successive grants without which what we did would not have been possible. My NC has always been my great support.

    KL: Kashmir is India’s main apple basket. Have you worked on apple scab?

    KZM: For Kashmir, agriculture is the backbone, especially the apple. The scab results in almost 30-40 per cent loss in apple. To prevent it we use around Rs 325 crore worth of fungicides which eventually go into our bodies through water and food. That is why people living around apple orchards have a higher incidence of endocrine-related issues.

    We have worked on biotechnological approaches to scab pathogens in which we have identified new genes that can be used for producing cisgenic apples for scab resistance. This study was also published in one of the reputed high-impact journals. We used comparative transcriptome technology (RNA-Seq) for research that showed some genes expressed in the Maharaji apple and wild-type genotypes like Florina are not expressed in red delicious, so these genes can be transferred into red delicious to make the variety scab resistant. The process of producing cisgenic apples and breeding both techniques is underway.

    KL: You have also identified some new wilt-causing pathogens. Tell us something about this.

    KZM: One of my PhD scholars, Dr Tasmeen Parihar has identified six new Fusarium spp infecting solanaceous crops that were not earlier known to cause wilt in chilli, brinjal, tomato and capsicum. These findings came out recently in reputed journals.

    We have many scientists in collaboration within and outside institutes. I am lucky to have good collaborations with Dr Zahoor A Bhat (Plant Pathology), Dr Khalid Bhat (Fruit Science), Dr Khursheed (Vegetable Sciences), Prof Mudasir Andrabi (Animal Biotechnology), Dr Tawheed Amin (FST) and many more.

    KL: There is a major ethical debate regarding biotechnology, especially GM foods.

    KZM: In biotechnology, we always have to face challenges related to transgenic plants but the fact is that in the near future (2050) breeding techniques will not be able to fulfil the need of the growing population. We will have to move towards biotechnology to feed the growing population of around 10 billion.

    CRISP-Cas technology will enable us to knock out the antibiotic genes used in transgenic progress and we will have transgenic plants with only the gene of interest and not these antibiotic-resistant genes. Besides, we also use recombinant-based excision repair to make Cisgenic Apple. Since this research is going on we will have soon some good results.

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    ( With inputs from : kashmirlife.net )

  • UPSC Interview Details of various posts

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    UPSC Interview Details of various posts

    Dated: 10-3-23

    For Interview Details of various posts click link below:

    Interview Details: 06 posts of Sub Divisional Engineer (Civil), Engineering Department, Chandigarh

    Interview Details: 02 posts of Sub Divisional Engineer (Public Health), Engineering Department, Chandigarh

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    [ad_2] #UPSC #Interview #Details #posts( With inputs from : The News Caravan.com )

  • India EXIM Bank 2023 – Manager & Management Trainee Interview Call Letter Released

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    India EXIM Bank 2023 – Manager & Management Trainee Interview Call Letter Released

    Name of the Post : India Exim Bank Management Trainee & Manager 2022 Interview Call Letter Released

    Total Post : 45

    India Exim Bank has Given an Employment Notification for the Recruitment of Management Trainee & Manager Vacancy on Direct Recruitment Basis.

    Important Links

    Interview Call Letter : Click here

    Interview schedule : Click here 

     

    JKPSC Fresh Govt Recruitment for 285 Posts

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    [ad_2] #India #EXIM #Bank #Manager #Management #Trainee #Interview #Call #Letter #Released( With inputs from : The News Caravan.com )

  • Musk takes ‘exit interview’ of sacked employee on Twitter

    Musk takes ‘exit interview’ of sacked employee on Twitter

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    San Francisco: Elon Musk on Twitter has taken an exit interview of a sacked worker, who asked him to confirm if he is still an employee or not.

    Ex-Twitter employee named Haraldur Thorleifsson wrote in his post: “Dear @elonmusk, 9 days ago the access to my work computer was cut, along with about 200 other Twitter employees. However, your head of HR is not able to confirm if I am an employee or not. You’ve not answered my emails. Maybe if enough people retweet you’ll answer me here?”

    To which Musk replied: “What work have you been doing?”

    Thorleifsson then talked about his job and the specific work he was doing at Twitter.

    After a brief discussion, the Twitter boss laughed at him with emojis, indicating that he had been fired.

    Moreover, the exit interview has gone viral, with many people finding Musk’s attitude rude and disrespectful.

    “Publicly humiliated his ex-employee. The guy had one shot and tried to waffle by saying he saved $500k on FIGMA,” a user wrote.

    “I’m sorry to say it doesn’t seem to be an actual question but him mocking you, someone who was just laid off. This makes me so upset I will probably cancel my subscription. I cannot support such a cruel organization. Explain yourself Elon!,” another user commented.



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    #Musk #takes #exit #interview #sacked #employee #Twitter

    ( With inputs from www.siasat.com )

  • University of Srinagar, Interview Notification 2023

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    University of Srinagar, Job Recruitment 2023

    The interview of the eligible candidates for the post of Contractual Lecturers available in the below mentioned departments shall be conducted in the Conference Room 2nd Floor, New Administrative Block, as per the following schedule

    The eligible candidates are advised to bring all the original qualification/degree certificates, testimonials, publications etc. with them at the time of interview. No individual call letters will be served in this regard. For further details, please log into the University website www.kashmiruniversity.ac.in.

    Further Details : 

    university of kashmir

     

    JKPSC Fresh Govt Recruitment for 285 Posts

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    [ad_2] #University #Srinagar #Interview #Notification( With inputs from : The News Caravan.com )

  • JKPSC Releases Interview Notice Of Candidates – Check Name List Here – Kashmir News

    JKPSC Releases Interview Notice Of Candidates – Check Name List Here – Kashmir News

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    Jammu and Kashmir Public Service Commission (JKPSC) has released Interview Notice for the post of Assistant Legal Remembrancer/District Litigation Officer in Department of Law, Justice & Parliamentary Affairs, notified vide Notification No. 21-PSC(DR-P) of 2022 dated 29.08.2022.

    News WhatsApp Group Links – Join Now

    The interview of the following candidates for the posts of Assistant Legal
    Remembrancer/District Litigation Officer in Department of Law, Justice & Parliamentary Affairs, notified vide Notification No. 21-PSC(DR-P) of 2022 dated 29.08.2022 will be held as per the schedule given below the Office of Jammu and Kashmir Public Service Commission, Resham Ghar Colony, Bakshi Nagar, Jammu.

    CHECK HERE LIST OF CANDIDATESWhatsApp Image 2023 03 03 at 20.45.42 WhatsApp Image 2023 03 03 at 20.46.14 WhatsApp Image 2023 03 03 at 20.46.28 WhatsApp Image 2023 03 03 at 20.46.59

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    #JKPSC #Releases #Interview #Notice #Candidates #Check #List #Kashmir #News

    ( With inputs from : kashmirnews.in )

  • IRCON International Limited 2023 Site Manager Interview Result Released

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    IRCON International Limited 2023 Site Manager Interview Result Released

    Name of the Post : IRCON International Ltd Site Manager 2022 Interview Result Result

    Total Post : 16

    IRCON International Limited has Given an Employment Notification for the Recruitment of Site Manager Vacancy on Contract Basis.

    Important Links

    Interview Result : Click here 

    JKPSC Fresh Govt Recruitment for 285 Posts

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    [ad_2] #IRCON #International #Limited #Site #Manager #Interview #Result #Released( With inputs from : The News Caravan.com )