Tag: dementia

  • Dementia Capital

    Dementia Capital

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    With Jammu and Kashmir recording the highest prevalence of dementia across India, the researchers are desperate to find answers to a trend that many think has leapt out of the mass depression the region has lived with, reports Insha Shirazi

    A recent study shocked the scientific community by revealing that Jammu and Kashmir top the list of areas in India having the highest prevalence of dementia. Published by the Journal of the Alzheimer’s Association, the study prevalence of dementia in India: National and state estimates from a nationwide study put the dementia prevalence in the 60-plus population in India at 7.4 per cent.

    What set the alarm bells ringing was that the prevalence of dementia was 4.5 per cent in Delhi and 11 per cent in Jammu and Kashmir.

    Alarmed over the findings, the scientists have started asking for more investigation to determine whether the long-running insurgency in Jammu and Kashmir, which has raged for more than 30 years, may be the cause of the area’s high dementia prevalence.

    In Jammu and Kashmir in general and Kashmir in particular, cases of dementia are stated to be on the rise. In 1986, a few years before the onset of militancy, a study on the prevalence of Alzheimer’s disease in Kashmir found no cases of dementia in Kashmir.

    Changed Situation

    Now the situation has completely changed.

    “We routinely see 3 to 5 cases of dementia-like cases in our daily OPD, on average,” Dr Yasir Rather, professor in the Department of Psychiatry, IMHANS GMC Srinagar said. “Brain cell destruction is the root cause of dementia. The communication between brain cells is disrupted as a result of this injury. Memory, thinking, behaviour, and feelings might be impacted when brain cells are unable to communicate correctly.”

    Off late, people with chronic dementia are more visible. “I regularly observed the activities of my grandmother, who has dementia. She is in her late 70s and exhibited strange behaviours, including forgetting my name and whether or not she had eaten lunch,” a university student, Alya said. “She used to converse with herself as if someone else were around, and sometimes, my grandmother’s condition worsened.”

    anxiety, dementia, kashmir mind, tension
    Brain Blast; Kashmir is witnessing a hugely above-average number of dementia patients and experts are exploring the possibility if it has links with the protracted conflict.

    The term dementia refers to a spectrum of mental impairments, including memory loss, difficulty speaking or understanding, difficulty solving problems, and another cognitive decline that is severe enough to affect a person’s ability to go about their everyday activities. This spectrum includes several different varieties of dementia, with Alzheimer’s disease being the most prevalent.

    There are two types of dementia. Vascular dementia, dementia with Lewy bodies, and frontotemporal dementia are irreversible. Reversible types include dementia-like conditions triggered by vitamin deficiency like vit B 12 or B 1 or due to thyroid problems. “Most people develop Alzheimer’s disease after the age of 65, but people under this age can also develop it,” Dr Yasir said. “This is called early-onset Alzheimer’s disease, a type of young-onset dementia. Dementia-like Frontotemporal type has been diagnosed in people in their 50s, 40s and even in their 30s.”

    “The early signs and symptoms of dementia will vary depending on the progression,” Dr Yasir said. “At the onset, the person may experience challenges with their short-term memory, and struggle with things such as paying the bills, preparing meals, forgetting names and religious ritual timings and household chores, or getting lost in a known area. With a moderate stage, an individual may have trouble speaking or understanding speech and they may not understand spatial awareness. In severe stages, a person will no longer have the ability to communicate and will be unable to care for themselves.

    High Prevalence

    What is, however, not known is why Kashmir offers a high percentage of people with dementia. The likely reasons, Dr Yasir said could include genetic predisposition, poor nutrition, lack of access to healthcare, and environmental factors such as water and air pollutants like excessive use of  agricultural and horticulture pesticides in our region.

    Besides, he said, Kashmir may have a greater prevalence of dementia due to the high rates of chronic stress, depression, and other psychological problems in the population. Moreover, the prevalence was greater in rural areas (8.4 per cent) than in urban areas (5.3 per cent), highlighting the urgent need to increase diagnosis in rural health facilities.

    Dr Kamran Nisar, a researcher at the University of Kashmir’s Centre of Research for Development, is working on the prevalence of Alzheimer’s disease in Kashmir. Alzheimer’s dementia, he said, is the most prevalent type of dementia, accounting for 70-80 per cent of the cases.

    Kamran has also been trying to find answers. He said a lot of factors contribute to dementia, which includes prolonged stress, conflict, floods, and separation from loved ones. Besides, dementia is also impacted by dietary choices, physical inactivity and family history. People who engage in physical activities, such as cycling, have a far lower risk of developing dementia than physically inactive people.

    “In Kashmir, there is a small amount of awareness about dementia, and as a result, people frequently misunderstand what dementia is and how it differs from forgetfulness or some other age-related condition,” Dr Kamran said. “We need to address this issue as much as we can because no awareness campaigns or events are being organized at the university or college level about this dementia and its prevalence is rising in Kashmir.”

    Neurologist Dr Irfan Yousuf, also asserted that Kashmir lacks basic knowledge about understanding the crisis. “There is a lack of knowledge about dementia and people mistakenly think it is a form of depression, even though these are unrelated conditions,” Dr Yousuf said. “A person with dementia acts normally and is unaware that they are afflicted with the illness, unlike a person with depression, whose mood is not always good, and who skips interactions as well.”

    Alzheimer’s disease is a neurodegenerative condition in which brain cells (nerve cells) are not operating normally. Vascular dementia occurs when the brain’s blood arteries get blocked, preventing appropriate blood flow and leading to neuronal dysfunction.

    Chronic Depression

    Kashmir has been the capital of mental sickness for a long time. For many decades, Kashmir has reported massive mental morbidity. Nearly 18 lakh adult residents of Kashmir, which is almost 45 per cent of the entire population, showed symptoms of mental distress, according to the 2015 survey by the Médecins Sans Frontières (MSF, or Doctors Without Borders). The survey revealed that 41 per cent of the population showed signs of depression, 26 per cent exhibited signs of anxiety, 23 per cent depression and anxiety and 19 per cent showed probable symptoms of post-traumatic stress disorder (PTSD), 17 per cent have depression and PTSD, 18 per cent have anxiety, depression and PTSD and 14 per cent have anxiety and PTSD.

    Debating Depression
    depression

    Though mental healthcare has expanded over the years and has a better spread, in comparison to the 1990s, the situation is still seriously challenging. The increasing incidence of drug abuse has added yet another load factor to the mental health system.

    Detecting Dementia

    Dr Irfan Yousuf said the first signs of dementia are when a family member or guardian notices that the person is repeating the same dialogue over and over again and that their mental activities are completely different and are not functioning properly. It is possible to alleviate symptoms and halt the progression of dementia, he said. Studies on dementia have been conducted, and the treatment is still ongoing.

    Psychiatry 2
    This is the core team that literally rebuilt the Government Psychiatric Diseases Hospital Srinagar that is now known as IMHANS.

    “A patient with advanced dementia forgets the route of the road where he or she frequently travels. Particularly at night, they lose track of how to get to their kitchen and bathroom,” Dr Yousuf said. “Although the person suffering from dementia is unaware of these symptoms, family members and their attendants have seen changes.”

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    ( With inputs from : kashmirlife.net )

  • High BP in men in their 30s linked with dementia risk in their 70s

    High BP in men in their 30s linked with dementia risk in their 70s

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    New Delhi: Having high blood pressure in your 30s is associated with worse brain health around age 75 like high dementia risk, especially for men, a new study has revealed.

    The research, published in JAMA Network Open, found that the high blood pressure group had significantly lower regional brain volumes and worse white matter integrity. Both factors are associated with dementia.

    The researchers from University of California-Davis Health compared magnetic resonance imaging (MRI) brain scans of older adults who had high blood pressure between the ages of 30 to 40 with older adults who had normal blood pressure.

    MS Education Academy

    The research also showed that the negative brain changes in some regions — such as decreased grey matter volume and frontal cortex volume — were stronger in men.

    The differences may be related to the protective benefits of estrogen before menopause.

    “Treatment for dementia is extremely limited, so identifying modifiable risk and protective factors over the life course is key to reducing disease burden,” said Kristen M. George, an assistant professor in the Department of Public Health Sciences.

    High blood pressure is an incredibly common and treatable risk factor associated with dementia.

    “This study indicates hypertension status in early adulthood is important for brain health decades later,” George added.

    Compared to participants with normal blood pressure, the brain scans of those transitioning to high blood pressure or with high blood pressure showed lower cerebral gray matter volume, frontal cortex volume and fractional anisotropy (a measure of brain connectivity).

    The scores for men with high blood pressure were lower than those for women.

    The study joins a growing body of evidence that cardiovascular risk factors in young adulthood are detrimental to late-life brain health.

    “This study truly demonstrates the importance of early life risk factors, and that to age well, you need to take care of yourself throughout life — heart health is brain health,” said Rachel Whitmer, senior author of the study.

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    #High #men #30s #linked #dementia #risk #70s

    ( With inputs from www.siasat.com )

  • Over 10 million older adults in India likely have dementia: AI study

    Over 10 million older adults in India likely have dementia: AI study

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    New Delhi: More than 10 million older adults aged 60 or over in India may have dementia, comparable to the prevalence rates for countries such as the US and the UK, according to a first-of-its-kind study.

    Dementia leads to impairment of mental processes, such as memory, thinking, reasoning and judgement, and thus seriously impairs an individual’s ability to perform daily functions.

    According to a study published in the journal Nature Public Health Emergency Collection, by 2050 people over 60 years of age are predicted to constitute 19.1 per cent of the total population in India.

    This ageing of the population is expected to be accompanied by a dramatic increase in the prevalence of dementia, a syndrome not taken very seriously in the country.

    The latest research, published in the journal Neuroepidemiology, used an artificial intelligence (AI) technique known as semi-supervised machine learning to analyse data from 31,477 older adults.

    The international team of researchers found that the prevalence rate of dementia in adults aged 60 or over in India could be 8.44 per cent — equating to 10.08 million older adults in the country.

    This compares to prevalence rates recorded in similar age groups of 8.8 per cent in the US, 9 per cent in the UK and between 8.5 and 9 per cent in Germany and France, they said.

    The prevalence of dementia was greater for those who were older, was females, received no education, and lived in rural areas, the researchers found.

    “Our research was based on the first and only nationally representative aging study in India with more than 30,000 participating older adults in the country,” said Haomiao Jin, co-author of the study and Lecturer in Health Data Sciences at the University of Surrey, UK.

    “AI has a unique strength in interpreting large and complex data like this, and our research found that the prevalence of dementia may be higher than prior estimates from local samples,” Jin said in a statement.

    The research team from the University of Surrey, University of Southern California, University of Michigan, both in the US, and All India Institute of Medical Sciences, New Delhi developed an AI learning model.

    The model was trained on data, which consisted of 70 per cent labelled dataset with dementia diagnoses from a novel online consensus.

    The remaining 30 per cent of the data was reserved as a test set to assess the AI’s predictive accuracy.

    The AI taught itself to predict dementia status for unlabelled observations without dementia diagnoses in the dataset.

    “As we are seeing with this research, AI has a huge potential to discover patterns in complex data, improving our understanding of how diseases impact people across very different communities to support the development of precision medical interventions to save lives,” Professor Adrian Hilton, Director of the University of Surrey’s Institute for People-Centered AI, added.

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    ( With inputs from www.siasat.com )

  • Bruce Willis diagnosed with dementia, family says

    Bruce Willis diagnosed with dementia, family says

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    Bruce Willis, who retired from acting last May as a result of aphasia, has been diagnosed with frontotemporal dementia, his family announced on Thursday.

    In a statement posted to the website for the Association for Frontotemporal Degeneration, the Die Hard actor’s family – wife Emma Heming, ex-wife Demi Moore and daughters Rumer, Scout, Tallulah, Mabel and Evelyn – revealed Willis’s aphasia had progressed into a diagnosis of dementia. Problems with language and memory, which instigated rumors about his cognitive state and prompted his retirement in May 2022, are “just one symptom of the disease Bruce faces”, they wrote.

    “While this is painful, it is a relief to finally have a clear diagnosis.”

    The statement continued: “FTD is a cruel disease that many of us have never heard of and [which] can strike anyone. For people under 60, FTD is the most common form of dementia, and because getting the diagnosis can take years, FTD is likely much more prevalent than we know.

    “Today there are no treatments for the disease, a reality that we hope can change in the years ahead. As Bruce’s condition advances, we hope that any media attention can be focused on shining a light on this disease that needs far more awareness and research.”

    Willis, who got his start in TV on Moonlighting, was one of the most bankable action stars of the 1980s and 1990s, known for the Die Hard franchise, Pulp Fiction, The Fifth Element, The Last Boy Scout, Twelve Monkeys, The Sixth Sense, Looper and Moonrise Kingdom. The 67-year-old was also the lead in several family comedies, most notably voicing a baby on Look Who’s Talking and its sequel.

    Willis had continued his action career in the years leading up to his retirement, though with diminishing returns – in 2021, the Razzies, the annual awards given to the year’s worst films, instituted a category for “worst performance by Bruce Willis in a 2021 movie”. It rescinded the award following his aphasia diagnosis.

    The family said in the statement: “Bruce always believed in using his voice in the world to help others, and to raise awareness about important issues both publicly and privately.

    “We know in our hearts that – if he could today – he would want to respond by bringing global attention and a connectedness with those who are also dealing with this debilitating disease and how it impacts so many individuals and their families.”

    The family also called for more awareness and understanding of frontotemporal dementia. They said: “Bruce has always found joy in life – and has helped everyone he knows to do the same. It has meant the world to see that sense of care echoed back to him and to all of us.

    “We have been so moved by the love you have all shared for our dear husband, father, and friend during this difficult time. Your continued compassion, understanding, and respect will enable us to help Bruce live as full a life as possible.”

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    ( With inputs from : www.theguardian.com )